Validation of Gene Expression Patterns for Oral Feeding Readiness: Transcriptional Analysis of Set of Genes in Neonatal Salivary Samples

口服喂养准备的基因表达模式验证:新生儿唾液样本中一组基因的转录分析

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作者:Leonardo Henrique Ferreira Gomes, Andressa Brito Marques, Isabel Cristina de Meireles Dias, Sanny Cerqueira de O Gabeira, Tamara Rosa Barcelos, Mariana de Oliveira Guimarães, Igor Ribeiro Ferreira, Letícia Cunha Guida, Sabrina Lopes Lucena, Adriana Duarte Rocha

Background

Neonatal health assessment is crucial for detecting and intervening in various disorders. Traditional gene expression analysis

Conclusions

In summary, the genes AMPK, FOXP2, WNT3, NPHP4, NPY2R, and PLXNA1 play critical roles in regulating oral feeding and the development of premature infants. Understanding the influence of these genes can provide valuable insights for improving nutritional care and support the development of these vulnerable babies. Evidence suggests that saliva-based gene expression analysis in newborns holds great promise for early detection and monitoring of disease and understanding developmental processes. More research and standardization of protocols are needed to fully explore the potential of saliva as a noninvasive biomarker in neonatal care.

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