A case report of oral contraceptive misuse induced cerebral venous sinus thrombosis and dural arteriovenous fistula

口服避孕药滥用诱发脑静脉窦血栓形成和硬脑膜动静脉瘘的病例报告

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Abstract

RATIONALE: Consumption of oral contraceptive pills (OCP) is a known risk factor for cerebral venous sinus thrombosis (CVST) among women. Development of dural arteriovenous fistula (dAVF) afterwards was very uncommon. We present a rare chronic complication of development of dAVF after CVST. PATIENT CONCERNS: A 22-year-old woman suffered headache for a week. She was then admitted into our hospital. DIAGNOSIS: Contrast enhanced magnetic resonance venography (MRV) demonstrated the thrombosis of the left transverse-sigmoid sinus the second day. INTERVENTIONS: The intravenous thrombolysis was carried out. As the symptoms improved, the patient was discharged, while the treatment with oral dabigatran continued. However, 3 months after the onset, magnetic resonance imaging (MRI) showed swelling brainstem, and digital subtraction angiography (DSA) confirmed a dAVF. Clipping of the fistula was conducted, and her clinical symptoms improved gradually. OUTCOMES: The patient was transferred to rehabilitation center later, and received follow-up care. LESSONS: When a patient taking OCP and suffering from a sudden headache, a clinical suspicion of possible CVST should always arise to avoid the onset of dAVF as soon as possible.

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