Abstract
BACKGROUND: Dengue fever (DF) is one of the most important arboviral diseases and causes significant morbidity and mortality worldwide. Healthcare professionals (HCps) play a crucial role in the prevention, diagnosis, and control of DF. This study aims to assess the knowledge, attitude, and practices (KAP) of HCPs regarding DF management in Kerman Province, southeastern Iran. MATERIALS AND METHODS: This cross-sectional analytical study was conducted from April to August 2024 in Kerman Province, southeastern Iran. Healthcare professionals (HCPs) from different occupational categories participated. Data were collected using a Persian online questionnaire (www.porsline.ir) covering demographic characteristics and KAP related to DF. The survey link was distributed via social media, email, and official channels. Data were analyzed using SPSS version 24, applying descriptive statistics and multivariable logistic regression, with statistical significance set at α = 0.05. RESULTS: A total of 307 HCPs participated, with most being female (73.9%) and aged 30-49 years (66.1%). Overall, 30.9% of participants demonstrated a high level of knowledge, with the highest proportion observed among central-level health professionals (41.4%). Additionally, 66.1% and 92.2% of participants scored favorable attitude and practices toward DF, respectively. Multivariable analysis showed that central-level HCPs had significantly higher odds of having good knowledge compared to peripheral staff (AOR: 2.12, 95% CI: 1.06-4.25, P = 0.03). CONCLUSION: This study revealed moderate knowledge but generally positive attitudes and strong preventive practices among HCPs in Kerman Province. Significant gaps were identified in transmission and vector control as well as inappropriate prescribing knowledge, underscoring the need for continuous medical education and dissemination of updated treatment guidelines. While central-level staff demonstrated higher knowledge, peripheral-level staff and specialists showed notable deficiencies, highlighting the importance of tailored training initiatives. Strengthening diagnostic confidence, community engagement skills, and evidence-based clinical management will be essential to enhance preparedness and ensure effective dengue prevention and control in this high‑risk region.