[Review of International Literature for the Prevention and Control of Carbapenem-resistant Enterobacterales Infections]

[碳青霉烯类耐药肠杆菌感染预防与控制的国际文献综述]

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Abstract

Carbapenem-resistant Enterobacterales (CRE) infection poses a significant global public health threat and is categorized as a class 2 notifiable infectious disease under national surveillance in the Republic of Korea. With an increasing trend in reported cases and the number of reporting medical institutions, the establishment of effective infection control measures is necessary to prevent the spread of CRE. Through extensive internet searches, we reviewed foreign CRE strategies and international health organizations’ guidelines on CRE infection control. As a result, we found that many advanced countries actively manage antibiotic resistance by establishing surveillance system databases. They collect and analyze data on CRE occurrences and patients’ clinical and diagnostic information at the government level, sharing specific CRE reporting criteria, management strategies, and guidelines. While pre-emptive isolation and disinfectant bathing are not included in Korean CRE infection control guidelines, these intervention strategies are recommended in international CRE guidelines. Future research needs to be conducted to assess their applicability and effectiveness in the Korean context, and practical plans should be formulated based on these findings to enhance the capacity to prevent and respond to CRE transmission.

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