Preoperative nutritional risk and adverse perioperative outcomes in children with congenital choledochal cysts: a retrospective cohort study

先天性胆总管囊肿患儿术前营养风险与围手术期不良结局:一项回顾性队列研究

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Abstract

BACKGROUND: Congenital choledochal cysts (CCC) are rare biliary anomalies associated with significant morbidity. The impact of preoperative nutritional status on surgical outcomes in pediatric CCC patients remains unclear. This study aimed to investigate this relationship, using a validated nutritional risk screening tool to stratify patients. METHODS: We conducted a retrospective cohort study of pediatric patients who underwent CCC excision with Roux-en-Y hepaticojejunostomy at a single center between January 2011 and September 2025. Nutritional risk was assessed within 24 h of admission using the Screening Tool for Risk on Nutritional Status and Growth (STRONG(kids)). Patients were categorized into moderate malnutrition risk group (MR) and high malnutrition risk group (HR). Propensity score matching (PSM) was employed to balance baseline characteristics. Perioperative outcomes were compared between groups. RESULTS: Among 208 included patients, 107 were stratified as HR and 101 as MR before PSM. After PSM, 91 matched pairs were analyzed. The HR group had significantly lower weight-for-age (WAZ), height-for-age (HAZ), and BMI-for-age z-scores (BAZ), along with lower preoperative hemoglobin, albumin, total protein, and higher bilirubin and GGT levels. Postoperatively, the HR group experienced longer abdominal drainage duration, delayed gastrointestinal recovery, higher inflammatory markers (WBC, CRP), worse liver function markers, and lower albumin and lymphocyte counts. The overall complication rate was significantly higher in the HR group, primarily driven by a greater incidence of cholangitis. CONCLUSION: Preoperative high nutritional risk, identified by the STRONG(kids) screening tool, is strongly associated with adverse perioperative outcomes in children undergoing CCC surgery. Routine nutritional screening may facilitate risk stratification and guide preoperative optimization.

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