Abstract
INTRODUCTION: This study aimed to explore the function and applicability of localized China acute seizure action plan (CASAP) in the management of out-of-hospital seizures in children with epilepsy, and to provide a theoretical basis and practical framework for further optimisation and promotion of this action plan. METHODS: A self-paired research design was employed. The CASAP was used to provide out-of-hospital seizure management guidance to the primary family caregivers of children with epilepsy. The children were followed up for six months after the intervention. RESULTS: Sixty two children aged 0-18 years participated. The M (P25, P75) of the total seizures in children with epilepsy within six months before intervention with CASAP was nine (3-169), which was lower than seven (0-20) within six months after intervention (P < 0.05). The M of the average duration of seizures before intervention was 1.5 (1.0-5.4), and 0.5 (0.0-1.0) after intervention (P < 0.001). After intervention, number of children with no emergency visits increased from 35 (56) to 47 (76%), and those with ≥1 emergency visit decreased from 27 (44) to 15 (24%); (P < 0.05). DISCUSSION: The results provide beneficial insights for out-of-hospital seizure management and improves health outcomes in children.