Analysis of Lipid Profile Parameters in COPD Patients and Their Correlation with Disease Severity

慢性阻塞性肺疾病患者血脂谱参数分析及其与疾病严重程度的相关性

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Abstract

AIM: To compare the status of lipid profile parameters in chronic obstructive pulmonary disease (COPD) patients with controls (without COPD) and its correlation with the severity of the disease. MATERIALS AND METHODS: At "Banaras Hindu University's Institute of Medical Sciences, Sir Sunderlal Hospital in Varanasi," a case-control study was carried out. Patients with COPD aged more than 40 years and presented to SS Hospital with an acute exacerbation were screened, and those who satisfied the inclusion and exclusion criteria were chosen for the study. Proper history and physical examination were done and complete blood count, lipid profile, renal function test, liver function test, high sensitivity C-reactive protein, arterial blood gas, spirometry, ECHO, and electrocardiogram were performed and data was collected and recorded for analysis. RESULTS: It was discovered that there was no statistically significant increase in the lipid profile characteristics of patients as compared to controls. Lastly, there was no discernible relationship between the patient's serum lipid profile and COPD based on data and statistics. Additionally, there was no statistically significant relationship found between the patient's serum lipid profile and the severity of their COPD. CONCLUSION: Although we did not identify a relationship between lipoproteins and the severity of COPD disease, more thorough research is needed to obtain reliable findings.

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