Corneal Surface Elevation and Thickness in Relation to the Fit of Rigid Contact Lenses in Keratoconus and After Corneal Cross-Linking

圆锥角膜患者及角膜交联术后角膜表面隆起度和厚度与硬性隐形眼镜适配性的关系

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Abstract

PURPOSE: To determine if factors pertaining to corneal thickness and elevation were linked to the prescribed back optic zone radius and overall diameter in keratoconus (group I), and cross-linked keratoconus (group II), cases successfully fitted with rigid contact lenses. PATIENTS AND METHODS: A review of cases adapted to contact lens wear (Rose K™) and assessed using Pentacam™ (for corneal anterior surface topography, astigmatism, elevation, and topographic thickness variation) was undertaken to determine the significance of any correlation with comfort, lens usage, grading of keratoconus, corrected distance visual acuity (with glasses and contacts), refractive error, prescribed lens powers, back optic zone radius and overall diameter values were assessed. RESULTS: Chief findings were, comfort was rated highly, lenses were worn for more than 10 hours/day in 75% of cases. RCL corrected distance logMAR acuities (median, mode, inter-quartile ranges) were 0.11, 0.12 (0.08-0.13) and 0.08, 0.08 (0.06-0.11) in groups I and II, respectively. Multiple linear regression revealed significant correlations (p<0.01) between the [A] back optic zone radius, the thinnest value of corneal thickness (x1) and anterior corneal surface elevation (x2). The respective r(2) values were 0.471 in group I and 0.512 in group II. [B] overall diameter, x1 and x2. The respective r(2) values were 0.282 in group I and 0.505 in group II. CONCLUSION: RCLs were well-tolerated in both groups. The r(2) values imply there is a 50% chance of correctly predicting the suitable back optic zone radius in both groups, a 50% chance of correctly predicting the overall diameter in group II and 28% in group I cases using just x1 and x2. The thinnest value of corneal thickness and anterior corneal surface elevation could be used to quickly select the BOZR and OD during RCL fitting. This has the potential to reduce chair-time, waste and improve efficiency.

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