Abstract
This study aimed to evaluate the effect of concentrated growth factor (CGF) gel on the repair of defects following the resection of giant skin tumors. Data were collected from patients who utilized CGF gel to fill the defects between January 2020 and June 2024, including records of drainage fluid, pain scores, time of drainage tube removal, discharge time, healing time, infection rates, and patient satisfaction. Data were analyzed using SPSS version 27.0. 58 patients were included in the study, comprising 35 males and 23 females. There were 32 patients in Group A (CGF with drainage) and 26 patients in Group B (drainage only). The postoperative healing time (11.5 ± 1.55 days), hospitalization duration (7.31 ± 0.90 days), and drainage tube removal time (4.03 ± 0.97 days) in Group A were significantly shorter than those in Group B. Additionally, the drainage volume on the third day (11.38 ± 2.51 mL) and the fifth day (1.42 ± 3.83 mL) postoperation were also lower in Group A compared to Group B (P < .05). The use of CGF gel significantly shortened healing and hospitalization times, reduced drainage fluid volume, and improved patients' satisfaction. Compared to conventional surgery, the application of CGF on postoperative defects of giant skin tumors deserves clinical promotion and popularization.