Dual treatment of hemichorea-hemiballismus syndrome with tetrabenazine and chemodenervation

采用丁苯那嗪和化学去神经支配双重治疗偏侧舞蹈症-偏侧投掷症

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Abstract

BACKGROUND: Hemichorea-hemiballismus involves unilateral involuntary flailing movements and random jerking movements involving proximal or distal muscles. We describe a case of hemichorea-hemiballismus with dystonia after stroke. Treatment with tetrabenazine and chemodenervation produced beneficial responses. Effective treatment of both hemichorea-hemiballismus and dystonia due to stroke has not been reported. CASE REPORT: A 65-year-old male developed left hemichorea-hemiballismus and dystonia after a right hemisphere stroke. He underwent initial treatment with neuroleptics and anticonvulsants without improvement. Subsequent treatment with tetrabenazine improved the hemichorea-hemiballismus and chemodenervation reduced the dystonia. DISCUSSION: Hemichorea-hemiballismus associated with dystonia can be improved with both tetrabenazine and chemodenervation.

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