Background
Canine neutrophils release neutrophil extracellular traps (NETs) in response to lipopolysaccharide but NETs from clinical septic dogs had not been identified. The primary
Conclusions
Immunofluorescence microscopy could be a useful tool for the study of NETs in dogs with clinical sepsis.
Results
NETs were identified and quantified in all cytology samples collected from septic dogs. A small number of NETs was documented in one dog with sterile chronic bronchitis. No NETs were found in sterile abdominal effusion collected from one dog with congestive heart failure. Conclusions: Immunofluorescence microscopy could be a useful tool for the study of NETs in dogs with clinical sepsis.