Abstract
This review summarizes the breakthrough studies on diabetes management in pregnancy presented at the 84(th) American Diabetes Association Scientific Sessions, encompassing 31 presentations, categorized into basic science, clinical studies, therapeutic interventions, and maternal/neonatal outcomes. Basic science investigations reported the enduring impact of gestational diabetes mellitus on offspring adiposity, neurodevelopment, transgenerational metabolic risk, and key insights on β-cell functioning and islet dysfunctioning. Clinical studies explored novel diagnostic and monitoring approaches, highlighting the potential of continuous glucose monitoring for early detection, risk prediction, and personalized management. Therapeutic interventions demonstrated the efficacy of glucagon-like peptide 1 agonists in preventing cognitive deficits in offspring. Maternal and neonatal health studies emphasized the critical role of optimal glycemic control, early gestational diabetes mellitus intervention, and risk stratification utilizing HbA1c and electronic heart records.