Diagnostic and prognostic value of adipose tissue content and distribution indicators for normal weight obesity in young women

脂肪组织含量和分布指标对年轻女性正常体重肥胖的诊断和预后价值

阅读:1

Abstract

The rise in global obesity and related health risks has highlighted the importance of precise body composition analysis, especially in individuals who appear healthy according to Body Mass Index (BMI). This study examines the diagnostic and prognostic significance of body composition indicators for assessing cardiometabolic risk in young women with normal weight obesity (NWO). The research included 330 women aged 18-24 years from northwestern Poland with normal BMI (18.5-24.9 kg/m(2)), using dual-energy X-ray absorptiometry (DXA) for detailed body composition assessment. A key achievement of the study was establishing a new cut-off point for body fat percentage (PBF) at 35.78%, which effectively identified individuals at increased cardiometabolic risk. Results showed that 27.3% of participants were classified as having NWO and exhibited higher insulin levels, increased HOMA-IR scores, and a lipid profile indicative of greater cardiometabolic risk, including elevated total cholesterol, LDL-C, non-HDL-C, and triglycerides, alongside reduced HDL-C levels. The android-to-gynoid (A/G) fat ratio emerged as a significant predictor, correlating positively with insulin resistance and negatively with HDL-C levels. These findings highlight the limitations of BMI and underscore the need for comprehensive body composition analysis. Identifying the NWO phenotype early could prompt preventive lifestyle interventions, even in those with a normal BMI.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。