Exploring a Possible Link Between Tinnitus and the Risk of Obstructive Sleep Apnea-A National Population-Based Cohort Study Using Propensity Score Matching Analysis

探索耳鸣与阻塞性睡眠呼吸暂停风险之间可能存在的联系——一项基于全国人口队列的倾向评分匹配分析研究

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Abstract

Objectives: The association between tinnitus and obstructive sleep apnea (OSA) has received attention; however, the mechanisms linking both conditions with diverse outcomes are still unclear. This study aimed to evaluate the association between OSA risk and tinnitus, including the OSA-related characteristics affecting tinnitus. Methods: We included participants aged 40-65 years with auditory examinations and STOP-BANG questionnaire between 2019 and 2021 from the Korean National Health and Nutrition Examination Survey data. Possible causative factors for tinnitus were identified using logistic regression analysis. Participants in the low- and high-risk groups for OSA were 1:1 matched using propensity score matching to compare the possible causative factors. Results: The high-risk group exhibited a higher incidence of tinnitus, persistence, and severity. However, when the causative factors of tinnitus were matched, no significant differences were observed. The most likely contributing factors were high-frequency hearing level in the worse ear for the experience and persistence of tinnitus and smoking for the severity of tinnitus. The high-risk group experienced tinnitus more often than the low-risk group, with no differences between the groups when tinnitus-affective factors were controlled. Conclusions: These findings suggest that tinnitus is unaffected by OSA itself but by the hearing loss that accompanies OSA.

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