Abstract
BACKGROUND AND AIMS: Globally, the emergence of the COVID-19 pandemic profoundly impacted cancer management. This review discusses the different perspectives on the effect of the pandemic on cancer care in Iran. METHODS: The literature search yielded 38 articles on cancer management in Iran during the COVID-19 pandemic. This study evaluated multiple aspects of cancer management, including screening, diagnosis, surgical and pharmacological management, palliative care, psychological aspects, telemedicine, cancer research, and guidelines and recommendations during the pandemic. RESULTS: Studies indicate that cancer patients are at a heightened risk of severe COVID-19 infections, with a high risk of requiring invasive ventilation, hospitalization in the ICU, and subsequent death. The pandemic significantly affected cancer screenings, in turn leading to a greater number of advanced disease presentations. Furthermore, some surgical and pharmacological treatments were deferred, complicating risk-benefit assessments resulted in complex and challenging decisions regarding patient care. Cancer patients experienced substantial psychological distress, which was exacerbated by delays in treatment and anxiety about contracting COVID-19. The commentary highlights the critical importance of adaptive measures, such as telemedicine and home-based palliative care, to minimize the effects of future health crises on cancer care. CONCLUSION: The significant impact of the pandemic on cancer care highlights the critical nature of ensuring that cancer care is a top priority during public health emergencies to achieve equitable access and quality patient care.