Long-term immunogenicity of hepatitis A virus vaccine in Alaska 17 years after initial childhood series

阿拉斯加地区儿童期接种甲型肝炎病毒疫苗17年后,疫苗的长期免疫原性情况

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Abstract

The Centers for Disease Control and Prevention recommends hepatitis A virus (HAV) vaccination for all children at age 1 year and for high-risk adults. The vaccine is highly effective; however, protection duration is unknown. We report HAV antibody concentrations 17 years after childhood immunization, demonstrating that protective antibody levels remain and have stabilized over the past 7 years.

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