Two new chiratane-type triterpenoids from Swertia kouitchensis

西瓜獐牙菜中两个新的菥蓂烷型三萜化合物

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作者:Luo-Sheng Wan, Ting-Ting Liu, Xiao-Jun Lin, Qiu-Xia Min, Jia-Chun Chen

Abstract

Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1-4 showed moderate inhibitory activity against the α-glucosidase (with IC₅&sub0; values ranging from 1,812 to 2,027 μM).

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