Preparation, loading, and cytotoxicity analysis of polymer nanotubes from an ethylene glycol dimethacrylate homopolymer in comparison to multi-walled carbon nanotubes

乙二醇二甲基丙烯酸酯均聚物聚合物纳米管的制备、负载和细胞毒性分析以及与多壁碳纳米管的比较

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作者:Ben Newland, Laurent Thomas, Yu Zheng, Martin Steinhart, Carsten Werner, Wenxin Wang

Abstract

Despite concerns over toxicity, carbon nanotubes have been extensively investigated for potential applications in nanomedicine because of their small size, unique properties, and ability to carry cargo such as small molecules and nucleic acids. Herein, we show that polymer nanotubes can be synthesized quickly and easily from a homopolymer of ethylene glycol dimethacrylate (EGDMA). The nanotubes formed via photo-initiated polymerization of the highly functional prepolymer, inside an anodized aluminium oxide template, have a regular structure and large internal pore and can be loaded with a fluorescent dye within minutes representing a simple alternative to multi-walled carbon nanotubes for biomedical applications.

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