Abstract
OBJECTIVE: Early detection of Parkinson's disease (PD) is essential for halting its progression, yet challenges remain in leveraging deep learning for accurate identification. This study aims to overcome these obstacles by introducing a hybrid deep learning approach that enhances PD detection through a combination of autoencoder (AE) and radial basis function neural network (RBFNN). METHODS: The proposed method analyzes the power spectral density (PSD) of preprocessed electroencephalography (EEG) signals, with artifacts removed, to assess energy distribution across EEG sub-bands. AEs are employed to extract features from reconstructed signals, which are subsequently classified by an RBFNN. The approach is validated on UC SanDiego's EEG dataset, consisting of 31 subjects and 93 minutes of recordings. RESULTS: The hybrid model demonstrates promising performance, achieving a classification accuracy of 99%. The improved accuracy is attributed to advanced feature selection techniques, robust data preprocessing, and the integration of AEs with RBFNN, setting a new benchmark in PD detection frameworks. CONCLUSION: This study highlights the efficacy of the hybrid deep learning framework in detecting PD, particularly emphasizing the importance of using multiple EEG channels and advanced preprocessing techniques. The results underscore the potential of this approach for practical clinical applications, offering a reliable solution for early and accurate PD detection.