A Rare Case of Giant Leiomyoma in the Space of Retzius

Leiomyoma are benign tumors of smooth muscle origin. Uterine leiomyoma are extremely common; leiomyoma in extraperitoneal spaces, however, are not. There have been several documented cases of leiomyoma in retroperitoneal spaces, though the majority of them have been in the posterior retroperitoneum. Here, we report a patient presenting with a large, firm suprapubic mass, initially thought to be a fundal uterine fibroid. On surgical excision, it was found to be the extremely rare finding of a benign leiomyoma in the anterior retroperitoneum or space of Retzius.