Abstract
Brucellosis, a zoonotic infection caused by Brucella species, typically manifests as a febrile illness with systemic involvement. Rare complications, such as splenic infarction, are less commonly encountered. We present a case of a 48-year-old female with prolonged fever and left hypochondrial pain. Diagnostic imaging and blood culture confirmed the diagnosis of brucellosis with splenic infarction. A tailored antibiotic regimen resulted in significant improvement. This case underscores the importance of timely diagnosis and management in endemic regions to prevent severe complications.