Abstract
OBJECTIVE: This study aimed to evaluate the efficacy of an MPNFS-based integrative psychological intervention for adolescents with anxiety disorders, focusing on anxiety symptoms, Self-Concept, Parenting Style, Family Intimacy, and Social Support. METHODS: A retrospective study was conducted on 196 adolescents (10-18 years) with anxiety disorders treated at Xiangxi Tujia and Miao Autonomous Prefecture People's Hospital from January 2024 to October 2025. Among them, 89 received routine outpatient care and 107 received a 6-week MPNFS-based integrative program as part of routine clinical care. Clinical outcomes included the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Piers-Harris Children's Self-Concept Scale (PHCSS), Egna Minnen av Barndoms Uppfostran (EMBU), Family Adaptability and Cohesion Scale II Chinese Version (FACESII-CV), Perceived Social Support Scale (PSSS), and Short Form 36 Health Survey (SF-36). RESULTS: Baseline characteristics were comparable between groups. After 6 weeks, the observation group demonstrated significantly greater improvements than the control group in anxiety (SAS: estimate = -7.5, 95% CI -8.6 to -6.4, P < 0.001) and depression (SDS: -7.4, 95% CI -8.5 to -6.3, P < 0.001). Self-concept improved across all PHCSS subscales (Behavior, Intellectual/School Status, Physical Appearance, Anxiety, Popularity, Happiness; total score: 18.0, 95% CI 16.9-19.1, P < 0.001). Parenting factors improved, including increased paternal emotional warmth (10.1, 95% CI 9.1-11.1, P < 0.001) and maternal emotional warmth (0.8, 95% CI 0.2-1.4, P = 0.012), along with reduced paternal punishment and rejection, and maternal over-interference/protection (all P < 0.001). Family functioning (FACESII-CV: 47.4, 95% CI 46.1-48.7, P < 0.001), perceived social support (PSSS: 20.2, 95% CI 19.0-21.4, P < 0.001), and all SF-36 domains showed significantly greater improvements in the observation group (all P < 0.001). CONCLUSION: The MPNFS-based integrative intervention effectively alleviates anxiety and depression, enhances self-concept, optimizes family functioning, strengthens social support, and improves quality of life in adolescents with anxiety disorders. These findings highlight the clinical potential of a structured multi-component approach and provide evidence supporting its adoption in routine outpatient care, while future longitudinal and randomized studies are needed to confirm the sustainability of these effects.