Cortical candidates for self-other distinction based on visual and action cues: where do we stand?

基于视觉和动作线索的自我-他人区分的皮层候选者:我们目前处于什么阶段?

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Abstract

Distinguishing sensations that were generated by one’s actions (reafference) from those that were not may be grounded in the comparison of sensory and action cues; i.e., in evaluating sensory movement feedback against motor predictions by “comparator” modules in the brain. For the evaluation of visual movement feedback, brain imaging studies have converged on three candidate brain regions for such comparisons: the EBA, the STS, and the AG. Yet, the question whether the “action cues” received by those regions are motor or non-motor signals cannot conclusively be answered, partly due to the heterogeneity of the imaging results and differences in experimental methodology. Thus, there is an ongoing debate which of these regions implement visuomotor comparisons, rather than merely intersensory (e.g., visuoproprioceptive) comparisons blind to the cause of movement. In this mini review, I revisit the assumptions of classical (visuomotor) comparator models; discuss potential experimental biases resulting from non-motoric cues; highlight how differences in kinematic predictability result from different kinds of experimental visual feedback distortion—and how this could be capitalized on; and I discuss the potential promises and pitfalls of recent experimental approaches using adaptation designs and factorial visuomotor conflict designs with additional control over the locus of movement generation.

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