Repetitive navigated transcranial magnetic stimulation to facilitate motor rehabilitation in acute pediatric hemorrhagic stroke - illustrative case

重复导航经颅磁刺激促进急性儿童出血性卒中患者运动功能康复——病例分析

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Abstract

BACKGROUND: Hemorrhage from arteriovenous malformations (AVMs) represents the most frequent cause of pediatric hemorrhagic stroke. However, outcomes often bear permanent extensive neurological impairments. OBSERVATIONS: An eleven-year-old male presented to the emergency department following a sudden onset of left-sided hemiparesis and continued loss of consciousness after an epileptic seizure. Imaging revealed a large hemorrhagic stroke of the right frontal lobe resulting from bleeding of an arteriovenous malformation. After microsurgical resection, low-frequency repetitive navigated transcranial magnetic stimulation (nrTMS) therapy targeting the motor hotspot of the unaffected hemisphere was administered. At the 4-month follow-up visit, the patient recovered motor function, with persisting minor deficits in leg mobility and a predominantly distant arm paresis. LESSONS: Utilizing nrTMS in pediatric patients effectively assessed motor function and in addition potentially contributed to early-stage motor rehabilitation. This method marks a potential advancement in acute pediatric stroke management.

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