Clinical features and prognosis in patients with coronary anomalies: the experiences and follow-up results of a single center

冠状动脉异常患者的临床特征和预后:单中心经验和随访结果

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Abstract

INTRODUCTION: Coronary anomalies (CAs) are rare congenital abnormalities often found incidentally on conventional coronary angiography (CCA), coronary computed tomographic angiography (CCTA), or autopsy. AIM: This study aimed to investigate the prevalence of origin and termination coronary artery anomalies via CCTA, and to evaluate outcomes over an 8-year follow-up. MATERIAL AND METHODS: To diagnose CAs, the CCTA data of 3017 consecutive patients who had undergone CCTA between January 2015 and January 2023 were analyzed retrospectively and followed up. RESULTS: Among the 3017 patients, 60 (2%) had coronary anomalies. Fifty-seven (95%) patients had origin and distribution anomalies, and 3 (5%) patients had a coronary artery fistula. The most common origin anomaly (13, 21.7%) was an anomalous origin of the right coronary artery (RCA), and the second one was (12, 20%) congenital atresia of the left main artery. It was also found that among anomalies, the most common (16, 26.6%) was the anomaly of course. Statistical analysis showed that the presence of CAs did not affect the development of major cardiovascular events (MACE) or mortality (p > 0.05). Kaplan-Meier analysis showed that the presence of CCA did not affect mortality (log-rank p = 0.516) or the development of MACE (log-rank p = 0.206). CONCLUSIONS: In this single-center study, the prevalence of CAs (2%) and the results of MACE and mortality were similar to those reported in the literature.

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