Comparison of drug-coated balloons and plain old balloon angioplasty in hemodialysis patients with Below-The-Knee artery disease

比较药物涂层球囊与普通球囊血管成形术在接受血液透析治疗的膝下动脉疾病患者中的应用

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Abstract

ObjectiveTo descriptively compare the clinical outcomes of drug-coated balloons (DCB) and plain balloon angioplasty (POBA) in hemodialysis patients with Below-The-Knee (BTK) peripheral artery disease.MethodsThis retrospective study included 96 hemodialysis patients (DCB:55 POBA:41). Outcomes included changes in Rutherford grade, wound healing, freedom from target lesion revascularization (CD-TLR), survival, and amputation-free survival.ResultsBoth groups demonstrated improvement in Rutherford grade at 12 months. Wound healing occurred in 60.6% (95% CI 42.1-76.8) of the DCB group and 50.0% (95% CI 32.0-67.9) of the POBA group. Amputation-free survival was 72.7% (95% CI 59.0-83.0) with DCB and 67.7% (95% CI 52.5-80.0) with POBA. Freedom from CD-TLR was 78.9% (95% CI 65.0-88.5) for DCB and 91.6% (95% CI 79.0-97.0) for POBA. No clear between-group differences were observed.ConclusionNo significant differences were observed between DCB and POBA in this small retrospective cohort.

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