Abstract
Chronic non-communicable diseases (NCDs) pose a significant global health burden, exacerbated by aging populations and fragmented healthcare systems. This study employs a comprehensive literature review method to systematically evaluate the integration of medical and preventive services for chronic disease management in the context of big data, focusing on pre-hospital risk prediction, in-hospital clinical prevention, and post-hospital follow-up optimization. Through synthesizing existing research, we propose a novel framework that includes the development of machine learning models and interoperable health information platforms for real-time data sharing. The analysis reveals significant regional disparities in implementation efficacy, with developed eastern regions demonstrating advanced closed-loop management via unified platforms, while western rural areas struggle with manual workflows and data fragmentation. The integration of explainable AI (XAI) and blockchain-secured care pathways enhances clinical decision-making while ensuring GDPR-compliant data governance. The study advocates for phased implementation strategies prioritizing data standardization, federated learning architectures, and community-based health literacy programs to bridge existing disparities. Results show a 30-35% reduction in redundant diagnostics and a 15-20% risk mitigation for cardiometabolic disorders through precision interventions, providing a scalable roadmap for resilient public health systems aligned with the "Healthy China" initiative.