Abstract
This guideline aims to standardize the prevention and management of complications related to umbilical venous catheterization (UVC). It addresses nine clinical questions, categorized into three sections: (1) questions concerning UVC-related infection, (2) catheter position, and (3) UVC maintenance. Literature screening and review were completed for all papers published up to May 31, 2025. Relevant evidence was synthesized through meta-analysis where applicable, and the GRADE methodology was applied to grade the quality of evidence and the strength of recommendations. The guideline establishes a total of nineteen recommendations and suggestions.