Integrating DFT Computations and QSAR Modeling to Predict Adsorption of Organic Pollutants onto Microplastics in Aqueous Environments

结合DFT计算和QSAR建模预测水环境中微塑料对有机污染物的吸附

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Abstract

Understanding the adsorption of organic pollutants onto microplastics in aqueous environments is crucial for assessing their environmental behavior and ecological risks. Herein, we used density functional theory (DFT) computations to simulate the aqueous adsorption of 54 organic compounds onto three representative microplastics, namely polyethylene (PE), polyoxymethylene (POM), and polyvinyl alcohol (PVA). Afterwards, based on theoretical molecular structural descriptors, we developed six quantitative structure activity relationship (QSAR) models based on datasets of 43 and 54 organic compounds, respectively. The results demonstrated that the oxygen-containing POM and PVA microplastics exhibited weaker adsorption in the aqueous phase compared to that in the gas phase. Furthermore, it revealed that the electron-rich atoms, van der Waals volumes and molecular polarizability exert substantial effects on the adsorption process on microplastics in water. These robust QSAR models can enable the prediction of adsorption energies for various organic pollutants on microplastics, which can offer a rapid approach for generating adsorption data. Moreover, the insights into adsorption mechanisms can provide a theoretical basis for designing modified or alternative plastics with lower environmental risks.

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