Clinical utility assessment framework for machine learning-based fetal health classification in cardiotocography: an observational study

基于机器学习的胎心监护胎儿健康分类临床实用性评估框架:一项观察性研究

阅读:1

Abstract

OBJECTIVE: To evaluate the clinical utility and implementation considerations of artificial intelligence (AI)-based fetal health classification systems using the Kaggle Fetal Health Classification dataset, with a focus on obstetric physicians' perspectives. METHODS: We analyzed the Kaggle Fetal Health Classification dataset (n=2,126), containing 21 cardiotocography parameters. Five machine-learning algorithms were evaluated: logistic regression, random forest, gradient boosting, support vector machine, and decision tree. Class weighting was applied to address the dataset imbalance. The model performance was assessed using standard classification metrics. An expert opinion-based clinical utility assessment framework was developed to assess interpretability, workflow integration, and safety. RESULTS: With class weighting applied, gradient boosting achieved the highest accuracy (89.67%), followed by random forest (88.50%) and logistic regression (82.16%). The most important predictive features were abnormal short-term variability (16.23% importance) and the percentage of time with abnormal long-term variability (13.21% importance). An analysis of all 21 features revealed that contraction-related parameters, including uterine_contractions, contributed minimally to the classification performance. The 35.3% false negative rate for pathological cases represents a significant safety concern and requires physician oversight. CONCLUSION: AI-based fetal health classification systems show potential for future applications when properly validated. However, the significant false negative rate for pathological cases indicates that these systems cannot function independently. External validation using multicenter clinical data and prospective outcome studies is essential before clinical implementation.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。