Abstract
To address the thermal management challenges in heterogeneous integrated chip design, this study proposed an intelligent thermal resistance prediction model that integrated physical mechanisms with a backpropagation (BP) neural network. Unlike traditional black-box data-driven approaches, the proposed method was grounded in fundamental heat transfer principles and systematically constructed a physics-informed feature set encompassing geometric configurations, material properties, power distribution, and boundary conditions. Domain knowledge was explicitly encoded into the neural network architecture by introducing a physics-constrained layer with weight sign constraints and an attention-based feature interaction layer. Within a multi-task learning framework, the model simultaneously optimized the prediction of total thermal resistance, maximum temperature, and temperature non-uniformity. Experimental results demonstrated that the proposed model significantly outperformed baseline methods on the test set. Specifically, the coefficient of determination (R(2)) for total thermal resistance prediction reached 0.982, with a mean squared error of 0.021 K(2)/W(2) and a mean absolute error of 0.103 K/W. For maximum temperature prediction, the R(2) value reached 0.969. Compared with a single-task model that predicted only total thermal resistance, the multi-task architecture improved the primary task performance by 0.004. This study provided a fast, accurate, and physically interpretable intelligent tool for chip thermal design, and offered a valuable practical example of physics-informed machine learning applied to complex engineering problems.