Biological Matrix-Assisted Apexification: A Case Report Using PRF and MTA in Immature Necrotic Teeth

生物基质辅助根尖诱导成形术:应用富血小板纤维蛋白和矿物三氧化物酶体树脂(MTA)治疗未成熟坏死牙的病例报告

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Abstract

It is challenging to treat an infected nonvital young permanent tooth endodontically because there is a lack of natural apical constriction. In order for the obturating material to be condensed, an apical barrier must be induced. Calcium hydroxide has historically been used to induce apexification. However, due to prolonged treatment time, multiple visits, and unpredictability in barrier formation, newer bioactive materials such as mineral trioxide aggregate (MTA) have been introduced for faster and more predictable outcomes. This case report presents the use of platelet-rich fibrin (PRF) as a biological internal matrix in conjunction with MTA for apexification of immature necrotic teeth. Although a single-visit procedure was initially planned, the presence of persistent exudate necessitated a multivisit approach to ensure thorough disinfection before final obturation.

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