Abstract
Immunodeficiency-related vaccine-derived poliovirus (iVDPV) was detected in the stool of a 5-year-old male patient with combined immunodeficiency. The patient presented in August 2019 with chronic diarrhea, fever, and generalized weakness. This case was identified concurrently with the 2019-2020 poliovirus outbreak in the Philippines. Antiviral therapy with pocapavir and remdesivir was administered but was unsuccessful in iVDPV clearance. The patient remained a chronic iVDPV excretor until his death in 2023.