Abstract
Introduction: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. Patient concerns: The patient was an older woman with low immune function but was not a transplant patient. Diagnosis: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. Interventions: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. Outcome: The patient's condition deteriorated and she eventually died of myocardial infarction. Conclusion: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.