Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe2O4/Zn-Fe Mixed Metal Oxides Nanocomposite

前列腺癌细胞对三元钛酸盐纳米管/CuFe2O4/Zn-Fe 混合金属氧化物纳米复合材料的摄取

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作者:Ahmed Ag El-Shahawy, S A Abdel Moaty, A H Zaki, Nada A Mohamed, Yasser GadelHak, R K Mahmoud, A A Farghali

Background

Certainly, there is a demand for stronger recognition of how nanoparticles can move through the cell membrane. Prostate cancer is one of the forcing sources of cancer-relevant deaths among men.

Conclusion

The prepared ternary nanocomposite was highly uptake by PC-3 cells and possessed cytotoxicity that was dose and time-dependent. To conclude, the study offered the potential of the investigated ternary nanocomposite as a promising prostate anticancer agent.

Results

The results revealed cellular uptake validity, cell viability reduction, ultra-structures alterations, morphological changes and membrane damage of PC-3 cells.

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