Abstract
BACKGROUND: High-energy tibial pilon fractures are complex and severe fractures that are associated with a high risk of infection following open reduction and internal fixation. Infection can negatively impact patient outcomes. AIM: To compare risk factors for postoperative infection after open reduction and internal fixation for a pilon fracture. METHODS: Among the 137 patients included, 67 developed a surgical site infection. Demographic, clinical, and surgical factors were compared between the two groups. A binary logistic regression analysis was used to determine the odds ratio (OR) and corresponding 95%CI for significant risk factors for postoperative infection. RESULTS: The distribution of pathogenic bacteria among the 67 patients who developed a surgical site infection was as follows: Gram-positive, 58.2% (n = 39); Gram-negative, 38.8% (n = 26); and fungal, 2.9% (n = 2). The following factors were associated with postoperative infection (P < 0.05): a Ruedi-Allgower pilon fracture type III (OR = 2.034; 95%CI: 1.109-3.738); a type III surgical incision (OR = 1.840; 95%CI: 1.177-2.877); wound contamination (OR = 2.280; 95%CI: 1.378-3.772); and diabetes as a comorbidity (OR = 3.196; 95%CI: 1.209-8.450). CONCLUSION: Infection prevention for patients with a Ruedi-Allgower fracture type III, surgical incision type III, wound contamination, and diabetes lowers the postoperative infection risk after surgical management of tibial pilon fractures.