Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen

使用胶原膜药物洗脱支架与塞来昔布联合皮下注射酮替芬减少关节纤维化

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作者:Afton K Limberg, Meagan E Tibbo, Christopher G Salib, Alex R McLaury, Travis W Turner, Charlotte E Berry, Anthony G Jay, Jodi M Carter, Brad Bolon, Daniel J Berry, Mark E Morrey, Joaquin Sanchez-Sotelo, Andre J van Wijnen, Matthew P Abdel

Significance

Current literature has demonstrated that arthrofibrosis may affect up to 5% of primary total knee arthroplasty patients. For that reason, novel pharmacologic prophylaxis and treatment modalities are critical to mitigating reoperations and revisions while improving the quality of life for patients with this debilitating condition.

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