Abstract
OBJECTIVE: Complications following total parathyroidectomy (TPTX) without autotransplantation adversely affect the prognosis of patients with secondary hyperparathyroidism (SHPT). This study aimed to identify preoperative risk factors of Clavien-Dindo grade ≥ II complications after TPTX in SHPT patients, and develop a visualized model to predict the risk of complications (≥ grade II). METHODS: Clinical data were retrospectively collected from SHPT patients who underwent TPTX at our center between January 2013 and March 2025. The cohort was chronologically divided into a training set (n=552) and a validation set (n=236) in a 7:3 ratio. Postoperative complication severity was assessed using the Clavien-Dindo classification system. Patients were stratified into two groups based on complication grade: a high-risk group (grade ≥II) and a low-risk group (grade