Analysis of the chemerin and resistin adipokines in children and adolescents

儿童和青少年趋化因子和抵抗素脂肪因子分析

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作者:Vanessa S Fontes, Kácia Mateus, Michele P Netto, Renata M S Oliveira, George L L Machado-Coelho, Ana Paula C Cândido

Conclusion

the adipokines analyzed presented a distinct profile in the groups of children and adolescents with eutrophic and overweight.

Methods

a cross-sectional epidemiological study was conducted with 234 students enrolled in public elementary schools in the city of Juiz de Fora / MG. Anthropometric evaluation, biochemistry, and blood pressure measurement were performed. Statistical analyzes included the Student-t or Mann-Whitney tests, Pearson or Spearman correlation, used according to the distribution of the variables, and linear regression analysis, by means of the evaluation of the effect of the independent variables on the serum levels of chemerin and resistin, adjusted for age and sex. For the data analysis, SPSS® software version 21.0 and STATA® version 10.1 were used, assuming a significance level of 5%.

Results

the concentrations of chemerin were higher in eutrophic individuals than in those with excess weight (p> 0.05). In contrast, levels of resistin were higher in the young with excess weight than in the eutrophic ones (p <0.05). In the multiple linear regression analysis, the levels of chemerin were associated with the values of resistin, systolic, and diastolic blood pressure. Resistance levels maintained association only with BMI and chemerin values.

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