Relationship between body water distribution and sarcopenia in older adults: a systematic review

老年人体液分布与肌肉减少症的关系:系统评价

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Abstract

OBJECTIVE: To examine potential relationships between body water distribution, assessed by bioelectrical impedance analysis (BIA), and sarcopenia in older adults. METHOD: This systematic review was conducted based on the methodological guidelines established by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Were Included observational studies exploring the relationship between intracellular water, extracellular water, and total body water – assessed by BIA and sarcopenia. The quality of the studies was assessed using the Joanna Briggs Institute (JBI) assessment tools and guidelines. RESULTS: Initially, 16,056 articles were identified, and 11 studies were considered eligible for inclusion. Among the studies analyzed, five studies used the ECW/TBW ratio, examining its association with aspects related to sarcopenia, such as muscle strength, loss of muscle mass and physical performance in the older adults. The results indicated that the proportions of extracellular/total body water (ECW/TBW) and extracellular/intracellular water (ECW/ICW) are associated with sarcopenia, muscle strength, loss of muscle mass, and physical performance in the older people. Studies suggest that these relationships may be useful for understanding muscle health and the impact of aging. Most studies presented high methodological quality (above 70%), indicating a low risk of bias. CONCLUSIONS: The findings of this systematic review indicate that imbalances in body water distribution, particularly in the ECW/TBW and ECW/ICW ratios, are consistently associated with sarcopenia, loss of muscle mass, reduced strength, and poorer physical performance in the older adults.

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