Mimicking Tissues in 3D-Printed Radiology Phantoms: Brand, Product, and Color of Printing Filaments Matter!

在 3D 打印放射学模型中模拟组织:打印耗材的品牌、产品和颜色都很重要!

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Abstract

Additive manufacturing enables the rapid fabrication of radiographic phantoms for X-ray and CT imaging, supporting applications such as patient simulation, dosimetry, imaging protocol optimization, and quality assurance. Polylactic acid (PLA) and acrylonitrile butadiene styrene (ABS) are among the most widely used printing polymers in phantoms; however, their X-ray attenuation properties can vary substantially among manufacturers, product lines within manufacturers, and even between colors of the same product. Cylindrical samples of 34 PLA filaments from 11 manufacturers and 13 ABS filaments from 9 manufacturers were evaluated for X-ray attenuation and energy dependence between 70 and 140 kV using a clinical CT scanner. Measured mass densities ranged from 1.17 to 1.34 g/cm(3) for PLA and 1.03-1.11 g/cm(3) for ABS. At 120 kV, Hounsfield unit (HU) values spanned 109 to 424 HU for PLA and -34 to 40 HU for ABS. Energy dependence, quantified as the HU at 70 kV minus HU at 140 kV, ranged from -29 to +172 HU for PLA filaments and -52 to -4 HU for ABS filaments. Identical products differing only in color showed HU variations from <2 HU to >90 HU at 120 kV, with no consistent pattern linking specific colors to highest or lowest attenuation. These findings demonstrate that 3D printing materials require individual characterization, as base polymer designation alone does not predict X-ray behavior accurately. The observed variability, however, enables the design of phantoms with tailored attenuation and energy-dependent contrast. Referring only to base polymers when specifying 3D printing materials for radiographic phantoms or suggesting printing materials as radiographic substitutes to mimic a specified tissue or reference material without naming the actual product, including color, is, thus, insufficient.

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