Optimizing dosimetric leaf gap parameters for radiation therapy: A comparative study using three diode-array verification tools and an ionization chamber

优化放射治疗剂量学叶片间隙参数:一项使用三种二极管阵列验证工具和电离室的比较研究

阅读:1

Abstract

BACKGROUND: The dosimetric leaf gap (DLG) value is a key parameter that affects dose calculation accuracy in radiotherapy when using the Eclipse treatment planning system. Diode array dosimeters are used to determine the optimal DLG value because they are convenient and fast, providing instant readout of planar dose distributions rather than a point dose. However, variations in gamma pass rates (GPRs) across devices, even for the same radiotherapy treatment plan, may lead to different DLG determinations. PURPOSE: To compare the optimal DLG values determined using three -diode array dosimeters with those obtained using an ionization chamber (IC) and to evaluate whether diode array dosimeters can reliably reproduce IC-based DLG values. METHODS: Optimal DLG values were determined for 6 MV, 10 MV, and flattening filter-free (FFF) beams using ArcCHECK, Delta4, and SRS MapCHECK. The results were compared with the IC-based values across all energies. Radiochromic films validated the IC-based DLG values. Twenty volumetric modulated arc therapy plans were recalculated using ten different DLG values. The results were compared with the measured data. Optimal DLG values were determined using global gamma criteria (3%/2 mm and 2%/2 mm), local gamma (1%/1 mm), and dose difference criteria. RESULTS: Verification with radiochromic film using IC-based optimal DLG values yielded an average GPR of 98.7 ± 2.3% under the 3%/3 mm criterion. The average DLG difference between the IC and diode array dosimeters was -0.35 ± 0.23 mm (range: -0.80 to 0.26 mm), based on various gamma and dose difference criteria. A DLG difference of -0.35 mm showed dose deviations ranging from 0.27% to 1.05% across all beams. Except for one criterion, no significant differences were observed. CONCLUSIONS: DLG differences between IC and diode array dosimeters resulted in approximately 1% dose discrepancies, which are within the clinically acceptable range. This finding indicates that ArcCHECK, Delta4, and SRS MapCHECK can determine DLG values comparable to those obtained with IC.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。