Abstract
This mini-review explores adaptive responses in organisms exposed to high radiation levels, drawing comparisons between Chernobyl's wildlife-specifically its darker-pigmented frogs-and residents of Ramsar, Iran, a region with high natural background radiation. Chernobyl's wildlife adaptations are not surprising, as substantial evidence in humans, demonstrates similar adaptation to high radiation levels. Studies reveal that mechanisms such as increased melanin production in frogs and enhanced DNA repair capabilities in Ramsar residents help mitigate radiation damage. These adaptations provide a framework for understanding resilience to environmental stressors and contribute to broader discussions on evolutionary survival mechanisms in extreme environments. By examining ecological and physiological responses across species, this review sheds light on radiation's role in natural selection and potential applications for environmental and radiobiological research.