Abstract
Herein, we report the first mechanochemical strategy for the Ru-catalyzed deoxygenative borylation of free phenols via C-O bond cleavage. This Ru-catalyzed phenolic borylation approach has been successfully extended to the Suzuki-Miyaura-type cross-coupling of phenols with aryl bromides. The protocol accepts a wide scope of phenolic substrates, allowing the synthesis of aryl pinacolboranes and biphenyl structures in excellent yields and serving as a better alternative to classical cross-coupling reactions in the context of pot, atom, and step economy synthesis.