Abstract
Thumb carpometacarpal (CMC) joint osteoarthritis is characterized by severe pain, reduced grip strength, and restricted thumb mobility. This condition is among the most prevalent forms of arthrosis, significantly impacting patients' daily activities and overall quality of life. Managing patients with coagulation disorders presents a particular challenge, as they are at increased risk for postoperative bleeding, infectious complications, and the potential need for revision surgery. Von Willebrand disease (VWD) type I, a disorder caused by a deficiency of Von Willebrand factor (VWF), can lead to prolonged blood clotting times. This case report demonstrates the successful management of bilateral CMC joint osteoarthritis in a patient with VWD type I using arthroplasty, emphasizing the importance of perioperative hematological management to prevent complications.