Cardiac Involvement Classification and Therapeutic Management in Patients with Duchenne Muscular Dystrophy

杜氏肌营养不良症患者的心脏受累分类和治疗管理

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Abstract

Duchenne muscular dystrophy (DMD) is an inherited myogenic disorder due to mutations in the dystrophin gene on chromosome Xp21.1. The clinical picture included peripheral muscle weakness, cardiomyopathy and chronic respiratory insufficiency. In this paper, the authors review cardiac involvement in patients with DMD, propose a cardiac impairment classification and discuss therapeutic management options.

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