Abstract
With social networking enabling the expressions of billions of people to be posted online, sentiment analysis and massive computational power enables systematic mining of information about populations including their affective states with respect to epidemiological concerns during a pandemic. Gleaning rationale for behavioral choices, such as vaccine hesitancy, from public commentary expressed through social media channels may provide quantifiable and articulated sources of feedback that are useful for rapidly modifying or refining pandemic spread predictions, health protocols, vaccination offerings, and policy approaches. Additional potential gains of sentiment analysis may include lessening of vaccine hesitancy, reduction in civil disobedience, and most importantly, better healthcare outcomes for individuals and their communities. In this article, we highlight the evolution of select epidemiological models; conduct a critical review of models in terms of the level and depth of modeling of social media, social network factors, and sentiment analysis; and finally, partially illustrate sentiment analysis using COVID-19 Twitter data.