Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

Dean 结构样品芯与线性惯性聚焦的串联集成,可增强粒子和细胞分选

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作者:Paul M Holloway, Jonathan Butement, Manjunath Hegde, Jonathan West

Abstract

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.

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