Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting
Dean 结构样品芯与线性惯性聚焦的串联集成,可增强粒子和细胞分选
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作者:Paul M Holloway, Jonathan Butement, Manjunath Hegde, Jonathan West
| 期刊: | Biomicrofluidics | 影响因子: | 2.600 |
| 时间: | 2018 | 起止号: | 2018 Jul 9;12(4):044104. |
| doi: | 10.1063/1.5038965 | 方法学: | Cell sorting |
| 研究方向: | 细胞生物学 | 细胞类型: | 其它细胞 |
Abstract
In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.
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