Cortical inhibition effect in musicians and non-musicians using P300 with and without contralateral stimulation

利用P300成分,在有无对侧刺激的情况下,研究音乐家和非音乐家的皮层抑制效应。

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Abstract

INTRODUCTION: Musicians have more robust and efficient neural responses in the cortical and sub-cortical regions, demonstrating that musical experience benefits the processing of both non-linguistic and linguistic stimuli. OBJECTIVE: This study aimed to verify P300's latency and amplitude behavioral using contralateral stimulation in musicians and non-musicians. METHODS: This was a case-control study. Subjects were divided in two groups: musicians, comprising 30 professional musicians, and non-musicians, comprising 25 subjects without musical experience. RESULTS: The present study showed that the musicians had lower latencies and higher amplitudes than the non-musicians in the P300 without contralateral noise. For the P300 amplitude values, the difference between groups persisted, and the musicians presented significantly higher amplitude values compared with the non-musicians; additionally, the analysis of the noise effect on the P300 response showed that the latency values were significantly increased in the musicians. CONCLUSION: The central auditory nervous system of musicians presents peculiar characteristics of electrophysiological responses probably due to the plasticity imposed by musical practice.

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