Abstract
This study analyzes and compares the clinical efficacy and safety of transurethral blue laser vaporization of the prostate (BL-PVP) and transurethral green laser vaporization of the prostate (GL-PVP) in the treatment of benign prostatic hyperplasia (BPH). A retrospective analysis was conducted on the clinical data of 97 patients with BPH who were treated at the Urology and Nephrology Department of Xi'an People's Hospital (Fourth Hospital of Xi'an) from June 2022 to June 2024. Patients were divided into 2 groups based on the surgical technique: the BL-PVP group (n = 46), which underwent transurethral BL-PVP, and the GL-PVP group (n = 51), which underwent transurethral GL-PVP. Additionally, patients were further categorized based on prostate volume into group A (medium volume, 30-80 mL) and group B (large volume, >80 mL). Perioperative indices and postoperative follow-up data were compared between the 2 groups. Both the BL-PVP and GL-PVP groups demonstrated significant improvements in International Prostate Symptom Score, maximum flow rate, and postvoid residual at 1, 3, and 6 months postoperatively, with overall comparable efficacy between the 2 procedures (P < .05). The BL-PVP group showed a significant advantage in bladder irrigation time, catheter indwelling time, and length of hospital stay, particularly in patients with medium prostate volume (P < .05). Furthermore, the BL-PVP group exhibited faster recovery of urinary control in the early postoperative period, with lower residual urine volume and symptom scores at 1 and 3 months compared with the GL-PVP group. BL-PVP demonstrates an advantage in preserving sexual function in patients with medium-sized prostates (P < .05). BL-PVP is a safe and effective surgical approach for the treatment of BPH, offering comparable therapeutic outcomes to GL-PVP, with notable advantages in postoperative recovery speed and early improvement in urinary control. Due to its precise vaporization effect and minimal thermal injury, BL-PVP demonstrates certain functional advantages, particularly for patients with a high demand for fast recovery and sexual function preservation. This study indicates that BL-PVP is a promising innovative treatment with significant clinical application potential, providing important guidance for selecting surgical options for BPH patients.